D. Hughes, in Reference Module in Life Sciences, 2017. The GFM1 gene provides instructions for making an enzyme called mitochondrial translation elongation factor G1.
Abstract.
G elongation factor mitochondrial 1. Abstract. All lanes : Anti-Elongation factor 1-gamma antibody (ab72368) at 1/3000 dilution (in PBS-T for 16 hours at 4°C) Lane 1 : Monkey kidney whole cell lysate overexpressing Elongation factor 1-gamma Lane 2 : COS7 whole cell lysate Lysates/proteins at 20 µg per lane. View protein in Pfam PF10587 EF-1_beta_acid, 1 hit PF00736 EF1_GNE, 1 hit SMART i View protein in SMART SM01182 EF-1_beta_acid, 1 hit SM00888 EF1_GNE, 1 hit Intra- and interspecies variations of the translation elongation factor 1-α ( Tef-1α) gene were evaluated as a new identification marker in a wide range of dermatophytes, which included 167 strains of 30 species.An optimized pan-dermatophyte primer pair was designed, and the target was sequenced. The human elongation factor 1 alpha (EF-1 alpha) first intron highly enhances expression of foreign genes from the murine cytomegalovirus promoter. Translation elongation factors perform critical functions in protein synthesis in all domains of life, including the delivery of aminoacyl-tRNAs into the ribosome, and the translocation of peptidyl-tRNA from the ribosomal A-site to the ribosomal P-site.
With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. This enzyme is found in cell structures called mitochondria, which are … In procaryotes it is called elongation factor Tu (EF-Tu) and in Eukarya and Archaea elongation factor 1 which is composed of several subunits. Normal Function. Kim SY(1), Lee JH, Shin HS, Kang HJ, Kim YS. This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Printable PDF Open All Close All.