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Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns. Most of them can experience behavioral and emotional problems, as well as school difficulties. Some males with KS have no obvious signs or symptoms while others may have varying degrees of cognitive, social, behavioral, and learning difficulties.
Life expectancy for patients with Klinefelter syndrome is reduced by five to six years. Klinefelter syndrome is one of the most common chromosomal disorders, occurring in one to two per 1,000 live male births. The latest research has shown that it has a small impact on life expectancy and reducing it between 3 and 5 years on average, but also depends on the care you received and the good control of the disease, reaching many people with Klinefelter syndrome to have a long life.
However, early death can result from iatrogenesis (complications arising from medicinal or cultural interventions, like surgeries or extreme rituals). This is possible with the early diagnosis and treatment. We have previously reported the overall mortality to be increased by 50% and life expectancy reduced by about five years. Genetic testing; Treatment. It is suspected that Klinefelter syndrome is underdiagnosed because mild cases may not be identified. The life expectancy of Klinefelter's syndrome is a little lower than that of a person without the disease. A research-based publication in 1985 showed that life expectancy for Klinefelter Syndrome reduces by 5 years as opposed to normal individuals, and the afflicting causes usually are aortic valve problems and tumor issues. Many people with KS are not diagnosed until they are adults, and it is believed that up to two thirds may never be diagnosed at all. It can affect physical and mental development. Klinefelter syndrome (47, XXY) is a condition that occurs in men who have an extra X chromosome, resulting in an XXY sex chromosome karyotype. Symptoms Life Expectancy . It is sometimes just called XXY.
To confirm the diagnosis, further invasive prenatal testing such as amniocentesis is required. 48,XXYY syndrome is a chromosomal condition, characterized by the presence of an extra X and Y chromosome in males, that causes medical and behavioral problems. Klinefelter Syndrome – Life Expectancy. Between 1 in 500 and 1 in 1,000 boys are born with Klinefelter's syndrome (KS). Some studies have shown that the average life span may be about 2 years shorter than the average life span of men in the general population.
Though children with Klinefelter syndrome may feel that they are “different” from others, there is a high chance that they can live a healthy and normal life. ... People with the condition have a nearly normal life expectancy. The syndrome can affect different stages of language, physical, and social development. Klinefelter's syndrome is a genetic condition that only affects males.
Adults with Klinefelter syndrome may also have primary Klinefelter syndrome, also known as XXY syndrome, is a condition in boys and men that’s caused by an extra X chromosome. It is estimated that 3,000 affected boys are born each year in the US. More Information. Affected males have an extra X chromosome. Klinefelter syndrome may be suspected during a noninvasive prenatal screening blood test. 48,XXYY can be considered a variant of Klinefelter syndrome.Individuals with 48,XXYY are usually considerably tall with small testes that do not function normally leading to infertility. Men with Klinefelter syndrome are expected to have a normal life expectancy. The causes of death in 466 X chromatin positive males (Klinefelter's syndrome) studied prospectively over the last 25 years have been analysed.
According to research, Klinefelter syndrome can shorten your life expectancy up to two years. Patients diagnosed at a younger age seem to have a shorter lifespan, possibly because diagnosis at an earlier age is associated with a more severe phenotype. Klinefelter Syndrome Life Expectancy. Klinefelter syndrome (KS) is a condition that occurs in males when they have an extra X chromosome. Generally, individuals suffering from this condition live to nearly the same age as healthy people. With ongoing medical development, unofficial sources have stated that the life expectancy has reduced by an average of 2.1 years. However, you can still live a long, full life with this condition. Klinefelter syndrome (KS), also known as 47,XXY or XXY, is the set of symptoms that result from two or more X chromosomes in males.
A highly significant increase in mortality from cerebrovascular disease was observed in the sub group considered to be most … In addition, the features of this condition vary and can overlap significantly with those of other conditions.